Potassium Ion

SCHEMBL9733126

O=C([O-])CCC(CC=Cc1cccnc1)CCCCNS(=O)(=O)c1ccc(Cl)cc1.[K+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	TBXAS1	P24557	20/20	1.00

▸	TBXA2R	P21731	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Potassium Ion SCHEMBL9733124	1.00	TBXAS1 (1.00)	TBXAS1TBXA2R
SCHEMBL9732152	0.92	TBXAS1 (0.85)	TBXAS1TBXA2R
SCHEMBL9732149	0.92	TBXAS1 (0.85)	TBXAS1TBXA2R
SCHEMBL9732871	0.90	TBXAS1 (0.81)	TBXAS1TBXA2R
SCHEMBL9732867	0.90	TBXAS1 (0.81)	TBXAS1TBXA2R
SCHEMBL9841629	0.80	TBXAS1 (0.84)	TBXAS1TBXA2R
SCHEMBL9709519	0.74	TBXAS1 (1.00)	TBXAS1TBXA2R
SCHEMBL9710116	0.74	TBXAS1 (1.00)	TBXAS1TBXA2R
SCHEMBL9733988	0.73	TBXAS1 (1.00)	TBXAS1TBXA2R
SCHEMBL9732801	0.72	TBXAS1 (0.82)	TBXAS1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5153214-A	Treating cardiovascular disorders	CIBA-GEIGY CORPORATION (US)	1992-10-06	—	—	US	disclosed
US-5025025-A	Cardiovascular disorders	CIBA-GEIGY CORPORATION (US)	1991-06-18	—	—	US	disclosed
EP-0405391-A1	Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof	CIBA-GEIGY AG (CH)	1991-01-02	—	—	EP	disclosed