Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734053 | 0.90 | MEN1 (0.47) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9734887 | 0.90 | MEN1 (0.47) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9733292 | 0.88 | MEN1 (0.45) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9733130 | 0.81 | HTR1A (0.43) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9734163 | 0.80 | HIF1A (0.48) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9733337 | 0.78 | HIF1A (0.38) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9734041 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9733634 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2AHIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL9734049 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9732976 | 0.76 | KMT2A (0.55) | MEN1KMT2AHIF1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | claimed |
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |