Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733351 | 0.87 | RXFP1 (0.31) | — | |
| SCHEMBL9734444 | 0.84 | ALDH1A1 (0.36) | MEN1MAPTKMT2A | |
| SCHEMBL9733395 | 0.84 | S100A4 (0.35) | RAB9A | |
| SCHEMBL9368399 | 0.84 | ABCC9 (0.34) | — | |
| SCHEMBL9737114 | 0.83 | F10 (0.38) | — | |
| SCHEMBL9732430 | 0.82 | F10 (0.32) | — | |
| SCHEMBL9146624 | 0.82 | NR1H4 (0.32) | NR1H4NPSR1MAPTPTGESCYP19A1 | |
| SCHEMBL9732982 | 0.81 | ALOX5 (0.38) | MEN1MAPTRAB9AKMT2A | |
| SCHEMBL9147909 | 0.81 | NR1H4 (0.33) | NR1H4NPSR1MAPT | |
| SCHEMBL9146948 | 0.78 | NR1H4 (0.34) | NR1H4NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |