Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807574 | 0.87 | DRD2 (0.47) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9592944 | 0.86 | DRD2 (0.46) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9731916 | 0.85 | KCNH2 (0.51) | KCNH2KCNJ1HTR1AHTR7 | |
| Methyl Alcohol SCHEMBL9591993 | 0.85 | DRD2 (0.45) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9807598 | 0.79 | SIGMAR1 (0.58) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9591965 | 0.78 | DRD2 (0.57) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9593272 | 0.78 | ADRA1D (0.57) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9592174 | 0.78 | ACHE (0.59) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9732081 | 0.77 | KCNH2 (0.61) | KCNH2KCNJ1DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9593896 | 0.77 | ADRA1D (0.56) | KCNH2DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112824-A | Benzofurazan compounds | MERCK & CO., INC. (US) | 1992-05-12 | — | — | US | disclosed |