Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND2 | P30279 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116829 | 0.69 | ADORA2B (0.33) | ADORA2BUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16638946 | 0.63 | ALDH1A1 (0.35) | ADORA2BLMNAUSP2ALDH1A1CYP1A2 | |
| SCHEMBL2610718 | 0.63 | ADORA2B (0.33) | ADORA2BUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9196786 | 0.61 | HCAR2 (0.36) | ALDH1A1 | |
| SCHEMBL12292807 | 0.60 | KDM4E (0.31) | — | |
| SCHEMBL9196781 | 0.59 | KDM4E (0.37) | — | |
| SCHEMBL9190063 | 0.59 | PIK3CG (0.36) | LMNAALDH1A1 | |
| SCHEMBL9190075 | 0.58 | PIK3CG (0.36) | LMNAALDH1A1 | |
| SCHEMBL9194837 | 0.57 | CDC7 (0.38) | ALDH1A1 | |
| SCHEMBL9196608 | 0.57 | AKR1B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |