Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733292 | 0.90 | MEN1 (0.45) | ALDH1A1SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL9734163 | 0.90 | HIF1A (0.48) | ALDH1A1HIF1AMEN1KMT2ACA2 | |
| SCHEMBL9733681 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL9733604 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACA2LMNA | |
| SCHEMBL9734002 | 0.83 | MALT1 (0.47) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9733850 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACA2CA1 | |
| SCHEMBL9733299 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9733487 | 0.81 | MALT1 (0.39) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9734017 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL9733701 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | claimed |
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |