Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097831 | 0.83 | MTNR1A (0.50) | ACP3SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9733971 | 0.81 | SLC6A9 (0.50) | SLC6A9PPARGPPARAACP3SLC6A2 | |
| SCHEMBL9856532 | 0.81 | SLC6A4 (0.58) | SLC6A9SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL9857350 | 0.81 | SLC6A9 (0.67) | SLC6A9SLC6A4 | |
| Hydrochloric Acid SCHEMBL9857132 | 0.80 | SLC6A4 (0.59) | SLC6A9SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL13204407 | 0.77 | SLC6A9 (0.63) | SLC6A9SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL9856746 | 0.76 | SLC6A9 (0.52) | SLC6A9PPARGPPARASLC6A2SLC6A4 | |
| SCHEMBL9857396 | 0.75 | SLC6A4 (0.54) | SLC6A9PPARGPPARASLC6A2SLC6A4 | |
| SCHEMBL1519602 | 0.73 | DPP4 (0.47) | PTPN1 | |
| SCHEMBL1519603 | 0.73 | DPP4 (0.47) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |