Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24052027 | 0.83 | RAB9A (0.71) | THRBDYRK1ASMN1; SMN2HDAC6NPC1 | |
| SCHEMBL31119848 | 0.82 | THRB (0.56) | THRBDYRK1ASMN1; SMN2HDAC6NPC1 | |
| SCHEMBL9305296 | 0.82 | PIK3CA (0.50) | SMN1; SMN2HDAC6NPC1RAB9AHDAC1 | |
| SCHEMBL2031602 | 0.81 | NPC1 (0.68) | SMN1; SMN2HDAC6NPC1RAB9AHDAC3 | |
| SCHEMBL9307022 | 0.80 | RAB9A (0.57) | SMN1; SMN2HDAC6NPC1RAB9AHDAC1 | |
| SCHEMBL9734495 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2HDAC6NPC1RAB9A | |
| SCHEMBL9306708 | 0.80 | NPC1 (0.49) | DYRK1ASMN1; SMN2HDAC6NPC1RAB9A | |
| SCHEMBL10760937 | 0.77 | NPC1 (0.47) | DYRK1ASMN1; SMN2HDAC6NPC1RAB9A | |
| SCHEMBL10880169 | 0.75 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9734400 | 0.75 | HPGD (0.56) | SMN1; SMN2HDAC6NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |