Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734416 | 0.85 | KCNA5 (0.56) | KCNA5ALDH1A1KMT2AMEN1DRD2 | |
| SCHEMBL9734873 | 0.80 | KDM4E (0.57) | KCNA5ALDH1A1KDM4ESMN1; SMN2DRD2 | |
| SCHEMBL9735195 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1TSHREPHX2 | |
| SCHEMBL9734398 | 0.79 | KCNA5 (0.55) | KCNA5DRD2DRD3 | |
| SCHEMBL9734496 | 0.76 | KMT2A (0.53) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL9735575 | 0.76 | RAB9A (0.56) | ALDH1A1KMT2AKDM4EMEN1EPHX2 | |
| SCHEMBL9737198 | 0.76 | NAMPT (0.54) | KMT2AMEN1SMN1; SMN2TSHRGAA | |
| SCHEMBL9735044 | 0.74 | TPSAB1 (0.46) | KMT2AMEN1SMN1; SMN2TSHREPHX2 | |
| SCHEMBL9734342 | 0.74 | HRH2 (0.55) | KCNA5DRD2 | |
| SCHEMBL17842360 | 0.74 | KDM4E (0.70) | KCNA5ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |