Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.36 |
| ▸ | CHRNG | P07510 | 2/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRND | Q07001 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506152 | 0.66 | P2RX7 (0.35) | SSTR1SSTR4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL9506159 | 0.66 | CHRNA1 (0.38) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL13700881 | 0.62 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3LSSL3MBTL1 | |
| SCHEMBL8938784 | 0.62 | LMNA (0.35) | SSTR1SSTR4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL28044887 | 0.60 | IDO1 (0.35) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL13231733 | 0.60 | GRIN2D (0.53) | SSTR1SSTR4SLC6A2LMNAL3MBTL1 | |
| SCHEMBL8267927 | 0.60 | AKT2 (0.49) | SSTR1SSTR4LSSLMNAL3MBTL1 | |
| SCHEMBL8959061 | 0.60 | TRPA1 (0.35) | SSTR1SSTR4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL13503880 | 0.59 | LSS (0.43) | SSTR1SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28527487 | 0.59 | TRPA1 (0.39) | SSTR1SSTR4SLC6A4SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114935-A | Antitussive agents | DR. KARL THOMAE GMBH (DE) | 1992-05-19 | — | — | US | claimed |
| US-5114935-A | Antitussive agents | DR. KARL THOMAE GMBH (DE) | 1992-05-19 | — | — | US | disclosed |