SCHEMBL9735575

SCHEMBL9735575

O=C1CCC(C(=O)N2CCN(C(=O)c3ccccc3Cl)CC2)N1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.56
RXFP1 Q9HBX9 1/20 0.55
GAA P10253 1/20 0.52
KMT2A Q03164 2/20 0.50
MGLL Q99685 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR2B P41595 1/20 0.50
MAPK14 Q16539 1/20 0.50
NAMPT P43490 2/20 0.49
HSD11B1 P28845 1/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
EPHX2 P34913 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735378 0.85 P2RX7 (0.51) NAMPTLMNA
SCHEMBL9737198 0.85 NAMPT (0.54) GAAKMT2ANAMPTMEN1POLB
SCHEMBL9734955 0.85 HTT (0.57) KMT2AMGLLCYP2C9CYP2C19HTR2B
SCHEMBL9734952 0.83 NAMPT (0.52) KMT2ANAMPTMEN1POLBALDH1A1
SCHEMBL9735195 0.81 ALDH1A1 (0.52) RAB9AKMT2ACYP2C9CYP2C19NAMPT
SCHEMBL9735854 0.81 KMT2A (0.58) KMT2AMGLLHSD11B1MEN1POLB
SCHEMBL7950882 0.80 NAMPT (0.51) KMT2ANAMPTMEN1POLBALDH1A1
SCHEMBL7950888 0.80 NAMPT (0.51) KMT2ANAMPTMEN1POLBALDH1A1
SCHEMBL10723816 0.78 RAB9A (0.80) RAB9ARXFP1GAAKMT2AMGLL
Fasoracetam SCHEMBL21177980 0.78 NAMPT (0.47) KMT2ANAMPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102882-A Nootropic agents NIPPON SHINYAKU CO., LTD. (JP) 1992-04-07 US disclosed