Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735575 | 0.85 | RAB9A (0.56) | LMNANAMPT | |
| SCHEMBL9735854 | 0.84 | KMT2A (0.58) | PARP1MAPT | |
| SCHEMBL9736130 | 0.79 | NAMPT (0.61) | LMNANAMPT | |
| SCHEMBL7950888 | 0.78 | NAMPT (0.51) | PARP1L3MBTL1TSHRNAMPT | |
| SCHEMBL7950882 | 0.78 | NAMPT (0.51) | PARP1L3MBTL1TSHRNAMPT | |
| SCHEMBL9735532 | 0.77 | PARP1 (0.49) | PARP1L3MBTL1MAPTTP53 | |
| SCHEMBL9734613 | 0.76 | GFER (0.50) | PARP1NAMPT | |
| SCHEMBL9734952 | 0.76 | NAMPT (0.52) | PARP1L3MBTL1NAMPT | |
| SCHEMBL14825147 | 0.75 | P2RX7 (0.62) | P2RX7L3MBTL1MAPTLMNATP53 | |
| SCHEMBL11957909 | 0.75 | MDM2 (0.48) | PARP1NAMPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |