Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RHOA | P61586 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866637 | 0.90 | ALDH1A1 (0.35) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL7868288 | 0.75 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL9735835 | 0.73 | ADRB2 (0.32) | TSHR | |
| SCHEMBL8391276 | 0.69 | — | — | |
| SCHEMBL9432002 | 0.69 | TSHR (0.36) | MEN1KMT2AALDH1A1CYP2C19TSHR | |
| SCHEMBL7616929 | 0.69 | MMP8 (0.40) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7870039 | 0.69 | KMT2A (0.37) | KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL8629910 | 0.67 | MME (0.32) | MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9523641 | 0.67 | PPARG (0.33) | MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10577812 | 0.66 | ABCB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030048-A1 | PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-10-03 | — | — | WO | disclosed |