Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740806 | 0.90 | TMEM97 (0.33) | — | |
| SCHEMBL11251517 | 0.79 | ALDH1A1 (0.37) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9735939 | 0.77 | NPSR1 (0.32) | — | |
| SCHEMBL9736833 | 0.77 | NPSR1 (0.32) | — | |
| SCHEMBL9734985 | 0.70 | CASP1 (0.37) | ALDH1A1 | |
| SCHEMBL11261872 | 0.68 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11263380 | 0.67 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9735772 | 0.66 | MAPT (0.40) | LMNA | |
| SCHEMBL9739830 | 0.66 | FAAH (0.30) | — | |
| SCHEMBL11255786 | 0.66 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |