Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735937 | 0.90 | ALDH1A1 (0.36) | — | |
| SCHEMBL9736833 | 0.79 | NPSR1 (0.32) | TMEM97SIGMAR1 | |
| SCHEMBL9735939 | 0.79 | NPSR1 (0.32) | TMEM97SIGMAR1 | |
| SCHEMBL9739830 | 0.75 | FAAH (0.30) | FAAH | |
| SCHEMBL9740265 | 0.69 | — | — | |
| SCHEMBL9740373 | 0.68 | CASP1 (0.33) | KCNA3FAAH | |
| SCHEMBL11251517 | 0.68 | ALDH1A1 (0.37) | — | |
| SCHEMBL9740476 | 0.66 | ALDH1A1 (0.32) | TMEM97SIGMAR1 | |
| SCHEMBL10349584 | 0.65 | PKM (0.37) | FAAH | |
| SCHEMBL10349742 | 0.64 | PKM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |