Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372031 | 0.85 | KDM4E (0.33) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9733368 | 0.83 | ALOX5 (0.36) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL9735940 | 0.82 | KDM4E (0.34) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9732959 | 0.78 | NSD2 (0.31) | PTGS1PTGS2PTGES | |
| SCHEMBL9735400 | 0.77 | KDM4E (0.35) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9734213 | 0.74 | PBRM1 (0.33) | NPSR1 | |
| SCHEMBL9736236 | 0.71 | KDM4E (0.33) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9733219 | 0.68 | LMNA (0.32) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9736241 | 0.68 | ALDH1A1 (0.35) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9740084 | 0.67 | CNR2 (0.36) | KDM4ENPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |