Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732736 | 0.90 | KDM4E (0.33) | RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9740084 | 0.85 | CNR2 (0.36) | ALOX5PDPK1CNR2RAB9ASMN1; SMN2 | |
| SCHEMBL9733370 | 0.83 | KDM4E (0.34) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL9733057 | 0.80 | PDPK1 (0.38) | ALOX5PDPK1CNR2RAB9ASMN1; SMN2 | |
| SCHEMBL9737906 | 0.80 | ALOX5 (0.35) | ALOX5PDPK1CNR2RAB9ASMN1; SMN2 | |
| SCHEMBL9735503 | 0.75 | ALOX5 (0.35) | ALOX5PDPK1CNR2RAB9ASMN1; SMN2 | |
| SCHEMBL9732982 | 0.70 | ALOX5 (0.38) | ALOX5PDPK1CNR2RAB9ASMN1; SMN2 | |
| SCHEMBL9735940 | 0.69 | KDM4E (0.34) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL2152461 | 0.68 | LMNA (0.51) | RAB9ASMN1; SMN2MAPTPOLBKMT2A | |
| SCHEMBL9733029 | 0.67 | ALDH1A1 (0.38) | CNR2RAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |