Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735503 | 0.85 | ALOX5 (0.35) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9735400 | 0.79 | KDM4E (0.35) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9737040 | 0.79 | NPSR1 (0.30) | — | |
| SCHEMBL9735577 | 0.76 | NPSR1 (0.33) | KDM4E | |
| SCHEMBL9735940 | 0.73 | KDM4E (0.34) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9733370 | 0.71 | KDM4E (0.34) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9736485 | 0.69 | IDO1 (0.32) | — | |
| SCHEMBL9735545 | 0.68 | — | — | |
| SCHEMBL9736934 | 0.66 | NPSR1 (0.33) | KDM4E | |
| SCHEMBL9736959 | 0.65 | KDM4E (0.33) | KDM4ELMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |