Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462559 | 0.81 | ALDH1A1 (0.58) | POLB | |
| SCHEMBL17149227 | 0.80 | L3MBTL1 (0.54) | ATMHCRTR1HCRTR2POLB | |
| SCHEMBL2273088 | 0.80 | POLB (0.46) | POLB | |
| SCHEMBL306737 | 0.79 | POLB (0.45) | HCRTR1HCRTR2POLB | |
| SCHEMBL17135963 | 0.79 | HCRTR1 (0.52) | ATMHCRTR1HCRTR2POLB | |
| SCHEMBL6380157 | 0.79 | ADRA1D (0.46) | ATMHCRTR1HCRTR2 | |
| SCHEMBL13545148 | 0.79 | MAPT (0.47) | POLB | |
| SCHEMBL6644379 | 0.79 | P2RX7 (0.56) | ATMHCRTR1HCRTR2 | |
| SCHEMBL2572955 | 0.79 | NAPRT (0.58) | ATMHCRTR1HCRTR2 | |
| SCHEMBL9735902 | 0.78 | MAPT (0.44) | HCRTR1HCRTR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506763-A1 | SITE-SPECIFIC RECOMBINATION OF DNA IN PLANT CELLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |