Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306737 | 0.79 | POLB (0.45) | MAPTGAATDP1BRD4BRPF1 | |
| SCHEMBL4406065 | 0.79 | NAPRT (0.58) | MAPTTDP1RIPK1LMNAL3MBTL1 | |
| SCHEMBL14626001 | 0.79 | RIPK1 (0.43) | MAPTTDP1RIPK1LMNAL3MBTL1 | |
| SCHEMBL26225817 | 0.79 | GAA (0.47) | MAPTGAATDP1BRD4BRPF1 | |
| SCHEMBL9736137 | 0.78 | ATM (0.53) | POLBHCRTR1HCRTR2 | |
| SCHEMBL949562 | 0.78 | TDP1 (0.50) | MAPTGAATDP1BRD4BRPF1 | |
| SCHEMBL17675088 | 0.78 | HSD11B1 (0.50) | MAPTGAATDP1POLBLMNA | |
| SCHEMBL9737760 | 0.78 | LMNA (0.56) | POLBRIPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL31081770 | 0.76 | TDP1 (0.49) | MAPTGAATDP1BRD4BRPF1 | |
| SCHEMBL18201 | 0.76 | TDP1 (0.57) | MAPTGAATDP1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |