Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 4/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737251 | 0.86 | HSD17B10 (0.34) | SMN1; SMN2IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL9737720 | 0.86 | TLR3 (0.34) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL9735711 | 0.81 | ALDH1A1 (0.31) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9736148 | 0.78 | XIAP (0.32) | XIAPSMN1; SMN2IDO1MEN1ALDH1A1 | |
| SCHEMBL9735180 | 0.74 | HTR2B (0.33) | XIAPSMN1; SMN2BACE1IDO1MEN1 | |
| SCHEMBL9736733 | 0.73 | IDO1 (0.34) | XIAPSMN1; SMN2IDO1SIRT2 | |
| SCHEMBL9736485 | 0.73 | IDO1 (0.32) | XIAPSMN1; SMN2IDO1 | |
| SCHEMBL9735574 | 0.72 | BACE1 (0.32) | BACE1MEN1ALDH1A1KMT2A | |
| SCHEMBL26759016 | 0.72 | MEN1 (0.34) | IDO1SIRT2MEN1ALDH1A1KMT2A | |
| SCHEMBL9736968 | 0.71 | IDO1 (0.38) | XIAPSMN1; SMN2IDO1ALDH1A1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |