Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | WNT3 | P56703 | 1/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736168 | 0.79 | TPSAB1 (0.55) | NAMPTGAATGM2TPSAB1TPSD1 | |
| SCHEMBL9737233 | 0.76 | L3MBTL1 (0.53) | NAMPTGAATGM2TPSAB1TPSD1 | |
| SCHEMBL9734538 | 0.76 | SMN1; SMN2 (0.56) | NAMPTGAANPC1RAB9APARP1 | |
| SCHEMBL13780326 | 0.76 | SMN1; SMN2 (0.56) | NAMPTGAANPC1RAB9APARP1 | |
| SCHEMBL9737216 | 0.73 | SMN1; SMN2 (0.48) | NAMPTGAANPC1RAB9APARP1 | |
| SCHEMBL9734867 | 0.73 | SMN1; SMN2 (0.53) | NAMPTGAANPC1RAB9APARP1 | |
| SCHEMBL9734496 | 0.72 | KMT2A (0.53) | NAMPTEPHX2LMNAPOLBMEN1 | |
| SCHEMBL9736108 | 0.72 | NAMPT (0.43) | NAMPTTGM2NPC1TPSAB1TPSD1 | |
| SCHEMBL2906610 | 0.71 | HDAC3 (0.46) | MAPTSMN1; SMN2 | |
| SCHEMBL9734863 | 0.70 | CYP2C9 (0.56) | GAALMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |