Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735809 | 0.85 | MEN1 (0.35) | MAPT | |
| SCHEMBL9194883 | 0.85 | PDE4A (0.36) | MAOB | |
| SCHEMBL9735586 | 0.84 | F10 (0.39) | KDM4E | |
| SCHEMBL9736905 | 0.84 | ALOX5 (0.39) | KDM4EMAPT | |
| SCHEMBL8085076 | 0.83 | NPSR1 (0.34) | NPSR1KDM4EMAPTMAOB | |
| SCHEMBL9737036 | 0.78 | NPSR1 (0.32) | NPSR1KDM4EMAPTMAOBXIAP | |
| SCHEMBL9735249 | 0.76 | POLB (0.33) | NPSR1KDM4EMAPT | |
| SCHEMBL8085392 | 0.72 | HTR1A (0.35) | MAOB | |
| SCHEMBL8085319 | 0.72 | PPIB (0.44) | KDM4EMAPTMAOB | |
| SCHEMBL9734960 | 0.72 | ABCC9 (0.36) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |