Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736266 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5828 | 0.72 | TDP1 (0.56) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12444133 | 0.72 | TDP1 (0.56) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL29482305 | 0.72 | TDP1 (0.56) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL17625895 | 0.72 | KMT2A (0.47) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7941772 | 0.72 | KMT2A (0.49) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8524494 | 0.71 | KMT2A (0.42) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| Hydrogen Sulfide SCHEMBL28228918 | 0.70 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28001936 | 0.70 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3799173 | 0.70 | CTSB (0.65) | MAPTALDH1A1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130430-A | Anxiety, sleep disorders or seizures | NEUROGEN CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |