Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichlorbenzuron SCHEMBL3663126 | 0.86 | CNR1 (0.54) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL9736809 | 0.82 | PTGS2 (0.53) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9737557 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9350242 | 0.78 | GCGR (0.58) | MAPTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9352624 | 0.77 | NPC1 (0.50) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7598432 | 0.77 | RAB9A (0.54) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9348629 | 0.76 | NPC1 (0.48) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11244841 | 0.76 | MAOA (0.51) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7605864 | 0.75 | KMT2A (0.61) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7603611 | 0.75 | RAB9A (0.50) | MAPTMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475506-A1 | Pharmaceutical formulation containing a benzoyl urea derivative | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-03-18 | — | — | EP | claimed |
| EP-0475506-A1 | Pharmaceutical formulation containing a benzoyl urea derivative | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-03-18 | — | — | EP | disclosed |