Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737676 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HPGDNPSR1USP2RAB9A | |
| SCHEMBL9733029 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HPGDSMN1; SMN2ATMNPSR1 | |
| SCHEMBL9737580 | 0.83 | SMN1; SMN2 (0.35) | ALDH1A1HPGDSMN1; SMN2USP2NPC1 | |
| SCHEMBL9737143 | 0.81 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2ATMNPSR1 | |
| SCHEMBL9739182 | 0.80 | ABCC9 (0.46) | SMN1; SMN2LMNATSHRCASP3 | |
| SCHEMBL9735138 | 0.80 | KMT2A (0.40) | ALDH1A1SMN1; SMN2RAB9APOLBTSHR | |
| SCHEMBL9738703 | 0.77 | CNR2 (0.38) | ALDH1A1SMN1; SMN2CNR2NPC1RAB9A | |
| SCHEMBL9735371 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2ATMNPSR1 | |
| SCHEMBL9147849 | 0.74 | NR1H4 (0.41) | ALDH1A1HPGDUSP2RAB9AMEN1 | |
| SCHEMBL9150608 | 0.74 | ABCC9 (0.41) | ALDH1A1HPGDSMN1; SMN2USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |