Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736607 | 0.83 | NOTUM (0.39) | HTR2AHTR2C | |
| SCHEMBL9736003 | 0.70 | HTR2A (0.34) | HTR2AHTR2CMAT2A | |
| SCHEMBL17907979 | 0.65 | PTGDR2 (0.39) | HTR2AHTR2C | |
| SCHEMBL13279458 | 0.63 | CCR9 (0.34) | HTR2AHTR2C | |
| SCHEMBL906087 | 0.62 | HTR2C (0.55) | HTR2AHTR2CMAT2A | |
| SCHEMBL5357231 | 0.62 | HTR2C (0.55) | HTR2AHTR2CMAT2A | |
| SCHEMBL906089 | 0.62 | HTR2C (0.55) | HTR2AHTR2CMAT2A | |
| SCHEMBL17907965 | 0.62 | HTR2A (0.48) | HTR2AHTR2CMAT2A | |
| SCHEMBL9735956 | 0.60 | NOTUM (0.62) | HTR2AHTR2CMAT2A | |
| SCHEMBL4039593 | 0.59 | HTR2A (0.48) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021678-A1 | LIPOXYGENASE INHIBITING PYRROLO [1,2a]INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |