Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734492 | 0.83 | MALT1 (0.35) | MALT1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9736303 | 0.79 | MALT1 (0.36) | MALT1ABCB1ABCC9ABCC8KCNJ11 | |
| SCHEMBL9737646 | 0.77 | SCN8A (0.33) | MALT1ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9733219 | 0.77 | LMNA (0.32) | MALT1ABCB1ABCC9LMNACYP3A4 | |
| SCHEMBL9735734 | 0.74 | MALT1 (0.35) | MALT1ABCB1ABCC9ABCC8KCNJ11 | |
| SCHEMBL9739182 | 0.71 | ABCC9 (0.46) | MALT1ABCB1ABCC9ABCC8KCNJ11 | |
| SCHEMBL9369702 | 0.69 | ABCC9 (0.35) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9734213 | 0.67 | PBRM1 (0.33) | MALT1 | |
| SCHEMBL9874277 | 0.66 | ABCC9 (0.53) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL31060528 | 0.66 | ABCC9 (0.53) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |