Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372031 | 0.83 | KDM4E (0.33) | LMNAKDM4ENPC1RAB9APGR | |
| SCHEMBL9737456 | 0.83 | ALDH1A1 (0.34) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9737646 | 0.80 | SCN8A (0.33) | PGRCYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL9735525 | 0.79 | KDM4E (0.33) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8090676 | 0.77 | PDE4A (0.35) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9737221 | 0.77 | MALT1 (0.35) | LMNAPTGDR2CYP3A4ALOX15ABCC9 | |
| SCHEMBL9736173 | 0.74 | LMNA (0.32) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9369702 | 0.68 | ABCC9 (0.35) | LMNAABCC9ABCB1 | |
| SCHEMBL7327762 | 0.67 | ABCC9 (0.54) | LMNAKDM4ECYP3A4ABCC9ABCB1 | |
| SCHEMBL9735910 | 0.66 | ABCC9 (0.42) | LMNAKDM4ECYP3A4ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |