Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735577 | 0.85 | NPSR1 (0.33) | MALT1KDM4E | |
| SCHEMBL9735903 | 0.81 | CNR2 (0.36) | LMNAMEN1CYP3A4KMT2A | |
| SCHEMBL9736303 | 0.79 | MALT1 (0.36) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9736173 | 0.78 | LMNA (0.32) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL9737221 | 0.74 | MALT1 (0.35) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9735603 | 0.73 | PDE4A (0.44) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9734492 | 0.73 | MALT1 (0.35) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8535332 | 0.71 | HTR2A (0.44) | MALT1MAOBHTR2AABCB1KCNE1 | |
| SCHEMBL9736978 | 0.70 | ABCC9 (0.43) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9194883 | 0.70 | PDE4A (0.36) | MALT1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |