Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382468 | 0.92 | ITGB3 (0.42) | ITGB3ITGA2BDGAT1ADRA1DADRA1A | |
| SCHEMBL9737986 | 0.84 | ADRA1D (0.43) | ITGB3ITGA2BDGAT1TP53L3MBTL1 | |
| SCHEMBL9737731 | 0.76 | TP53 (0.41) | ITGB3ITGA2BDGAT1TP53L3MBTL1 | |
| SCHEMBL7293806 | 0.76 | ITGB3 (0.36) | ITGB3ITGA2BDGAT1TP53L3MBTL1 | |
| SCHEMBL9382556 | 0.75 | ADRA1D (0.49) | ITGB3ITGA2BDGAT1PPARDADRA1D | |
| SCHEMBL7289335 | 0.72 | ITGB3 (0.33) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL467521 | 0.69 | ACHE (0.55) | DGAT1TP53L3MBTL1 | |
| SCHEMBL9385024 | 0.67 | HTR2C (0.47) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL29405721 | 0.67 | CYP19A1 (0.49) | ITGB3ITGA2BDGAT1L3MBTL1 | |
| SCHEMBL18321998 | 0.67 | CYP19A1 (0.49) | ITGB3ITGA2BDGAT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0394471-A1 | THIENOCYCLOHEPTAPYRIDAZINE COMPOUNDS AND MEDICINAL USES THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |