SCHEMBL9737619

SCHEMBL9737619

CCOc1cc(OCC)nc(N=C(N)S)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
ADRA2A P08913 2/20 0.35
MEN1 O00255 3/20 0.33
SMN1; SMN2 Q16637 4/20 0.32
RAD52 P43351 2/20 0.32
QRFPR Q96P65 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738143 0.80 L3MBTL1 (0.44) CRHBPCRHR2KMT2AALDH1A1KDM4E
SCHEMBL9738689 0.80 CRHBP (0.41) ADORA2BCRHBPCRHR2KMT2AALDH1A1
SCHEMBL1576650 0.69 NPC1 (0.62) KMT2AALDH1A1KDM4ECYP1A2MAPT
SCHEMBL6336311 0.69 ALDH1A1 (0.41) KMT2AALDH1A1KDM4EMAPTHPGD
SCHEMBL9740905 0.68 POLB (0.40) ADORA2BCRHBPCRHR2KMT2AALDH1A1
SCHEMBL10397626 0.67 TSHR (0.36) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL7464556 0.66 ALDH1A1 (0.55) KMT2AALDH1A1KDM4EMAPTHPGD
SCHEMBL3825486 0.66 MEN1 (0.42) KMT2AALDH1A1CYP1A2RAB9ANPC1
SCHEMBL1421836 0.66 SMN1; SMN2 (0.42) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL9737603 0.66 SMN1; SMN2 (0.40) KMT2AALDH1A1KDM4ECYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086177-A Chemical intermediate for herbicides BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed