Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | RAF1 | P04049 | 4/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737724 | 1.00 | HPGDS (0.56) | HPGDSCYP11B1CYP11B2RAB9ANPC1 | |
| SCHEMBL2125895 | 0.87 | MAPK1 (0.53) | RAB9ANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL2125898 | 0.87 | MAPK1 (0.53) | RAB9ANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL6468773 | 0.86 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6468772 | 0.86 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL30713348 | 0.74 | MAPT (0.54) | CYP1A2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7087392 | 0.74 | PTGS2 (0.48) | HPGDALDH1A1MAPK1LMNAALOX5 | |
| SCHEMBL9736817 | 0.73 | MAPK13 (0.71) | RAB9ANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL31668803 | 0.73 | CYP11B2 (1.00) | CYP11B1CYP11B2RAB9ANPC1CYP1A1 | |
| SCHEMBL9268248 | 0.73 | CYP11B2 (1.00) | CYP11B1CYP11B2RAB9ANPC1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |