Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433122 | 0.87 | F10 (0.40) | F10OPRM1OPRD1OPRK1BAZ2B | |
| SCHEMBL9733267 | 0.79 | HTR1A (0.38) | ALDH1A1 | |
| SCHEMBL9733195 | 0.77 | HRH4 (0.34) | F10HRH4 | |
| SCHEMBL9733318 | 0.76 | S100A4 (0.38) | F10PDK2TDP2HRH4NPC1 | |
| SCHEMBL9734695 | 0.76 | KMT2A (0.40) | F10PDK2TDP2ALDH1A1 | |
| SCHEMBL9733799 | 0.76 | MAPT (0.40) | KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9588567 | 0.75 | F10 (0.41) | F10BAZ2BBAZ2APDK2NPC1 | |
| SCHEMBL7277331 | 0.73 | F10 (0.40) | F10OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL10433092 | 0.73 | F10 (0.36) | F10 | |
| SCHEMBL8085330 | 0.71 | F10 (0.40) | F10OPRM1OPRK1BAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |