Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738659 | 0.90 | HPGD (0.38) | IGF1RGAAHPGDTP53SMN1; SMN2 | |
| SCHEMBL9737938 | 0.87 | HSP90AA1 (0.38) | IGF1RHPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL9737842 | 0.80 | LMNA (0.36) | GAAHPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL9738322 | 0.77 | HSP90AA1 (0.41) | GAAHPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL9738307 | 0.77 | LMNA (0.37) | GAAHPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL9738140 | 0.77 | HSP90AA1 (0.38) | HPGDMAPTHTTNPC1ALDH1A1 | |
| SCHEMBL9739131 | 0.75 | HCRTR1 (0.42) | HPGDSMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL9737076 | 0.75 | MAPK14 (0.43) | GAAHPGDMAPTHTTALDH1A1 | |
| SCHEMBL9737393 | 0.75 | ALDH1A1 (0.43) | HPGDMAPTALDH1A1RBP4TSHR | |
| SCHEMBL9739960 | 0.75 | HSP90AA1 (0.39) | HPGDMAPTHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |