Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737826 | 0.90 | IGF1R (0.44) | HPGDHTTTSHRIGF1RMAPT | |
| SCHEMBL9739131 | 0.86 | HCRTR1 (0.42) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL9737938 | 0.85 | HSP90AA1 (0.38) | HPGDIGF1RMAPTKMT2AMEN1 | |
| SCHEMBL9738366 | 0.80 | HCRTR1 (0.39) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL9737842 | 0.78 | LMNA (0.36) | HPGDHTTTSHRMAPTKMT2A | |
| SCHEMBL9738322 | 0.76 | HSP90AA1 (0.41) | HPGDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9738307 | 0.75 | LMNA (0.37) | HPGDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9738140 | 0.75 | HSP90AA1 (0.38) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL9737076 | 0.74 | MAPK14 (0.43) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL9737393 | 0.74 | ALDH1A1 (0.43) | HPGDTSHRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |