Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538022 | 0.80 | MAOB (0.44) | KDM4EALDH1A1L3MBTL1MAPTPTGS2 | |
| SCHEMBL7699767 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1HPGDMAPTCA9 | |
| SCHEMBL28334181 | 0.78 | CA12 (0.39) | ALDH1A1CA9CA12CA1CA2 | |
| SCHEMBL14775511 | 0.77 | LMNA (0.36) | L3MBTL1MAPTERN1POLBTSHR | |
| SCHEMBL10634123 | 0.76 | ACHE (0.42) | ACHEKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9509766 | 0.74 | TUBB4A (0.43) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL721861 | 0.73 | ACHE (0.65) | ACHEKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7621559 | 0.73 | ACHE (0.33) | ACHEMAPTCA9CYP3A4PTGS2 | |
| SCHEMBL11332872 | 0.73 | ACHE (0.44) | ACHEALDH1A1L3MBTL1MAPTCA9 | |
| SCHEMBL7874401 | 0.73 | SMN1; SMN2 (0.42) | KDM4EALDH1A1HPGDMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |