Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739967 | 0.98 | ALDH1A1 (0.43) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL6073610 | 0.86 | LGMN (0.46) | ALDH1A1L3MBTL1MAPTALOX15MEN1 | |
| SCHEMBL9739579 | 0.85 | CHKA (0.52) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL1419659 | 0.81 | PRMT6 (0.45) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL162889 | 0.75 | MTOR (0.45) | CHKA | |
| SCHEMBL11548897 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTALOX15MEN1 | |
| SCHEMBL3140104 | 0.73 | TERT (0.41) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL3143049 | 0.72 | ALDH1A1 (0.43) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL21681490 | 0.72 | TERT (0.40) | TERTALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL2094918 | 0.72 | ALDH1A1 (0.43) | TERTALDH1A1L3MBTL1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |