Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | ITK | Q08881 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101892 | 0.86 | HRH4 (0.47) | MEN1KMT2AHRH4CSNK1DMAPK14 | |
| SCHEMBL9738792 | 0.85 | TERT (0.41) | CHKATERTMEN1KMT2AUSP2 | |
| SCHEMBL9739967 | 0.83 | ALDH1A1 (0.43) | CHKATERTMEN1KMT2AUSP2 | |
| SCHEMBL1419659 | 0.77 | PRMT6 (0.45) | CHKATERTMEN1KMT2AUSP2 | |
| SCHEMBL6073610 | 0.72 | LGMN (0.46) | MEN1KMT2AUSP2TSHRLMNA | |
| SCHEMBL27955545 | 0.71 | MAPT (0.48) | LMNAMAPT | |
| SCHEMBL28281275 | 0.71 | CHKA (0.75) | CHKACDC7CDK9ADRB2NCF1 | |
| SCHEMBL49273 | 0.70 | CHKA (1.00) | CHKATERTADRB2NCF1PLD1 | |
| SCHEMBL4112616 | 0.70 | CYP1A2 (0.48) | MEN1KMT2ATSHRLMNACYP3A4 | |
| SCHEMBL3140104 | 0.70 | TERT (0.41) | CHKATERTMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |