Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.45 |
| ▸ | PARP1 | P09874 | 6/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856567 | 0.76 | DRD2 (0.39) | KDM4E | |
| Noroxyhydrastinine SCHEMBL564339 | 0.75 | KDM4E (1.00) | KDM4EPARP10PARP11PARP1F7 | |
| Noroxyhydrastinine SCHEMBL29745981 | 0.75 | KDM4E (1.00) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL9214155 | 0.68 | PARP10 (0.62) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL15466514 | 0.68 | PARP10 (0.62) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL24136646 | 0.68 | KDM4E (0.56) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL793729 | 0.68 | PARP10 (0.62) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL29600821 | 0.68 | KDM4E (0.56) | KDM4EPARP10PARP11PARP1F7 | |
| SCHEMBL11331651 | 0.68 | ALOX15 (0.34) | — | |
| SCHEMBL4715588 | 0.65 | PARP10 (0.53) | KDM4EPARP10PARP11PARP1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |