Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.37 |
| ▸ | BAD | Q92934 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630725 | 0.70 | NQO2 (0.41) | NQO2BADTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL4038926 | 0.68 | HTR3E (0.33) | NQO2HTR3EHTR3BHTR1AHTR1D | |
| SCHEMBL19776164 | 0.68 | NQO2 (0.49) | NQO2BADHTR3EHTR3BHTR1A | |
| SCHEMBL7431153 | 0.66 | ALDH1A1 (0.38) | NQO2BADTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL7428865 | 0.66 | ALDH1A1 (0.38) | NQO2BADTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL9741484 | 0.66 | HTR3E (0.37) | NQO2HTR3EHTR3BHTR1AHTR1D | |
| SCHEMBL10705461 | 0.65 | NQO2 (0.42) | NQO2BADTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL9739358 | 0.64 | CA2 (0.43) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL24149616 | 0.64 | KDM4E (0.48) | NQO2HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL403982 | 0.63 | BAD (0.49) | BADALDH1A1MAPK1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |