Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206942 | 0.80 | KDM4E (0.35) | HRH3MEN1POLBKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9740720 | 0.79 | KDM4E (0.34) | HRH3MEN1POLBKMT2AKDM4E | |
| SCHEMBL9739398 | 0.76 | MAOA (0.36) | HRH3ALDH1A1KDM4EMAPTHCN4 | |
| Hydrochloric Acid SCHEMBL9206975 | 0.74 | ALDH1A1 (0.35) | HRH3ALDH1A1 | |
| SCHEMBL9208020 | 0.74 | HCN4 (0.49) | HRH3MAPK1MAPTHCN4HCRTR1 | |
| Hydrochloric Acid SCHEMBL9739509 | 0.73 | CYP3A4 (0.49) | HRH3MAPTHCN4HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL9739344 | 0.73 | CYP3A4 (0.49) | HRH3MAPK1MAPTHCN4HCRTR1 | |
| SCHEMBL9205342 | 0.72 | KDM4E (0.38) | HRH3ALDH1A1KDM4EMAPTHCN4 | |
| Hydrochloric Acid SCHEMBL9739072 | 0.71 | FAAH (0.43) | MAPTHCN4HCRTR1HCRTR2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9739342 | 0.71 | CYP3A4 (0.49) | ALDH1A1POLBKDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |