Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9739301 | 0.82 | HRH3 (0.38) | KCNH2CYP3A4ALOX15DRD2KDM4E | |
| SCHEMBL9739396 | 0.81 | MAOA (0.35) | MAOAMAOBKCNH2DRD2HRH3 | |
| SCHEMBL9206942 | 0.79 | KDM4E (0.35) | HCN4MAPTCYP3A4ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL9215824 | 0.78 | MEN1 (0.42) | MAOAMAOBHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL9740720 | 0.78 | KDM4E (0.34) | HCN4MAPTCYP3A4ALOX15KDM4E | |
| SCHEMBL10722947 | 0.78 | HRH3 (0.39) | MAOBKCNH2DRD2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9208323 | 0.78 | DRD2 (0.43) | HTR1ADRD3DRD2KDM4E | |
| SCHEMBL9739382 | 0.76 | HRH3 (0.42) | HCN4MAPTCYP3A4ALOX15KDM4E | |
| SCHEMBL9739297 | 0.72 | HRH3 (0.48) | KDM4EALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL9206975 | 0.72 | ALDH1A1 (0.35) | DRD2ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |