Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741191 | 0.90 | CRHBP (0.44) | CRHBPCRHR2LMNAAHRHTT | |
| SCHEMBL9741157 | 0.88 | ALDH1A1 (0.39) | CRHBPCRHR2F2PRSS1PRSS2 | |
| SCHEMBL9739709 | 0.78 | CRHBP (0.54) | CRHBPCRHR2LMNAAHRHTT | |
| SCHEMBL9740218 | 0.77 | L3MBTL1 (0.44) | CRHBPCRHR2MPOLMNAAHR | |
| SCHEMBL9749087 | 0.73 | MEN1 (0.35) | KMT2A | |
| SCHEMBL9739737 | 0.72 | CRHBP (0.48) | CRHBPCRHR2F2LMNAAHR | |
| SCHEMBL9741160 | 0.70 | HCRTR1 (0.33) | CRHBPCRHR2LMNAAHRHTT | |
| SCHEMBL12553942 | 0.64 | ATP4A (0.38) | ATP4AATP4B | |
| SCHEMBL11300906 | 0.61 | KDM4E (0.49) | F2KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9621983 | 0.60 | CRHBP (0.59) | CRHBPCRHR2LMNAAHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |