Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740376 | 0.80 | TSHR (0.42) | HSP90AA1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL9740686 | 0.79 | HSD11B1 (0.41) | HSP90AA1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL9711152 | 0.78 | HSD11B1 (0.41) | HSP90AA1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5953621 | 0.77 | TDP1 (0.45) | KMT2AALDH1A1L3MBTL1TDP1AKR1B1 | |
| SCHEMBL9711193 | 0.73 | ALDH1A1 (0.46) | KMT2ACYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL13911244 | 0.73 | CXCR2 (0.49) | KMT2APOLBGAAALDH1A1MEN1 | |
| SCHEMBL27973914 | 0.72 | NPC1 (0.48) | KMT2APOLBGAAALDH1A1MEN1 | |
| SCHEMBL9711214 | 0.72 | HSD17B10 (0.46) | KMT2AALDH1A1MEN1MAPK1VCAM1 | |
| SCHEMBL7391512 | 0.72 | HPGD (0.46) | HSP90AA1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9711155 | 0.70 | ALDH1A1 (0.39) | KMT2AGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |