Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740376 | 0.86 | TSHR (0.42) | KMT2AMEN1HSP90AA1L3MBTL1MAPT | |
| SCHEMBL9711152 | 0.83 | HSD11B1 (0.41) | HSD11B1KMT2AHSP90AA1L3MBTL1ALDH1A1 | |
| SCHEMBL9739733 | 0.79 | HSP90AA1 (0.43) | HSD11B1KMT2AMEN1HSP90AA1L3MBTL1 | |
| SCHEMBL9740023 | 0.78 | PLCG1 (0.60) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL9652718 | 0.78 | ALDH1A1 (0.43) | HSD11B1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL9739903 | 0.78 | KMT2A (0.44) | HSD11B1KMT2AMEN1CA1CA2 | |
| SCHEMBL9711155 | 0.76 | ALDH1A1 (0.39) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL9740477 | 0.76 | AKR1B1 (0.40) | HSD11B1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL4247243 | 0.76 | PLCG1 (0.56) | HSD11B1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL9711252 | 0.76 | TSHR (0.36) | KMT2AMEN1L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |