Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742586 | 0.90 | HTT (0.38) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9742794 | 0.90 | HTT (0.40) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9742164 | 0.90 | CHRM5 (0.47) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9739008 | 0.85 | SMN1; SMN2 (0.55) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9739787 | 0.85 | CHRM5 (0.43) | HTTMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9739723 | 0.85 | LMNA (0.46) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9743860 | 0.83 | HTT (0.41) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9743436 | 0.83 | GRIN1 (0.39) | HTTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9738601 | 0.81 | CHRM5 (0.53) | MEN1KMT2AMAPTCHRM5NPC1 | |
| SCHEMBL9742140 | 0.81 | CHRM5 (0.49) | KMT2ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |