Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 9/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743342 | 0.85 | PSEN1 (0.40) | CHRM5MAPTMEN1KMT2AOPRM1 | |
| SCHEMBL9743551 | 0.85 | PSEN1 (0.40) | CHRM5MAPTMEN1KMT2AOPRM1 | |
| SCHEMBL9738615 | 0.85 | CHRM5 (0.46) | CHRM5PGRNPC1POLBMAPT | |
| SCHEMBL9739723 | 0.85 | LMNA (0.46) | CHRM5NPC1POLBMAPTMEN1 | |
| SCHEMBL9740279 | 0.85 | HTT (0.47) | CHRM5PGRNPC1POLBMAPT | |
| SCHEMBL9738601 | 0.84 | CHRM5 (0.53) | CHRM5NPC1POLBMAPTMEN1 | |
| SCHEMBL9741279 | 0.83 | PARK7 (0.43) | CHRM5NPC1POLBMAPTMEN1 | |
| SCHEMBL9739646 | 0.83 | CHRM5 (0.42) | CHRM5NPC1POLBMAPT | |
| SCHEMBL9742140 | 0.81 | CHRM5 (0.49) | CHRM5KMT2AOPRM1SLC6A9OPRD1 | |
| SCHEMBL9740491 | 0.81 | MEN1 (0.40) | CHRM5PGRNPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |