Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644669 | 0.79 | CASP1 (0.40) | CASP1 | |
| SCHEMBL9738423 | 0.76 | ALDH1A1 (0.40) | CASP1 | |
| SCHEMBL1409918 | 0.75 | SMN1; SMN2 (0.36) | CASP1 | |
| SCHEMBL7339256 | 0.75 | SMN1; SMN2 (0.36) | CASP1 | |
| SCHEMBL9128981 | 0.72 | CASP1 (0.46) | CASP1 | |
| SCHEMBL9736281 | 0.70 | PIK3CD (0.34) | — | |
| SCHEMBL9736737 | 0.65 | PIK3CD (0.34) | — | |
| SCHEMBL4665617 | 0.64 | MMP9 (0.33) | — | |
| SCHEMBL29573275 | 0.64 | ATM (0.42) | CASP1 | |
| SCHEMBL9740476 | 0.64 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| EP-0350211-A2 | Novel 6-amido-1-methyl carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |