Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735772 | 0.73 | MAPT (0.40) | TMEM97SIGMAR1 | |
| SCHEMBL9740265 | 0.71 | — | — | |
| SCHEMBL9739830 | 0.71 | FAAH (0.30) | — | |
| SCHEMBL6639842 | 0.69 | CA2 (0.36) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 | |
| SCHEMBL9129955 | 0.67 | — | — | |
| SCHEMBL4462470 | 0.64 | CA2 (0.41) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 | |
| SCHEMBL7154999 | 0.62 | CA2 (0.50) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 | |
| SCHEMBL18817541 | 0.62 | CA2 (0.50) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 | |
| SCHEMBL11023633 | 0.62 | ALDH1A1 (0.41) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 | |
| SCHEMBL4361938 | 0.61 | CA2 (0.45) | ALDH1A1NPSR1TMEM97SIGMAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| EP-0350211-A2 | Novel 6-amido-1-methyl carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |